Cox-17 (N8) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS2514-50, BS2514-100

Sizes: 50µl, 100µl

Swiss-Prot: Q14061

Host: Rabbit

Reactivity: Human

Applications: WB, IHC, IF

Background: Cytochrome c oxidase 17 (COX17) is a nuclear gene encoding an assembly protein necessary for proper COX apoenzyme-dependent mitochondrial respiration. The mammalian COX apoenzyme is a heteromer consisting of three mitochondrial genes that encode catalytic subunits and several nuclear genes that encode structural subunits. COX17 influences the recruitment of copper to the mitochondria for incorporation into the COX apoenzyme.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: COX17 (N8) polyclonal antibody detects endogenous levels of COX17 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Cox-17 (N8) pAb at 1:500 dilution
Lane 1: PC3 whole cell lysate (40ug)
Lane 2: HEK293T whole cell lysate (40ug)
Lane 3: Panc1 whole cell lysate (40ug)
Lane 4: H9C2 whole cell lysate (40ug)
Lane 5: AML-12 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of Cox-17 (N8) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Bioworld Molecular Weight: ~ 7 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Cytochrome c oxidase copper chaperone; COX17

Immunogen: Synthetic peptide, corresponding to the N-terminal of Human Cox-17.

Conjugate: Unconjugated

Modification: Unmodified