Seletracetam (Ucb 44212) is an analog of the antiepileptic agent Levetiracetam. Seletracetam is a small molecule SV2A modulator for the research of epilepsy.

Product information

CAS Number: 357336-74-4

Molecular Weight: 232.23

Formula: C10H14F2N2O2

Chemical Name: (2S)-2-[(4S)-4-(2,2-difluoroethenyl)-2-oxopyrrolidin-1-yl]butanamide

Smiles: CC[C@@H](C(N)=O)N1C[C@@H](CC1=O)C=C(F)F

InChiKey: ANWPENAPCIFDSZ-RQJHMYQMSA-N

InChi: InChI=1S/C10H14F2N2O2/c1-2-7(10(13)16)14-5-6(3-8(11)12)4-9(14)15/h3,6-7H,2,4-5H2,1H3,(H2,13,16)/t6-,7+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Seletracetam decreases seizure activity in a number of epilepsy models and binds to the synaptic vesicle protein SV2A. Seletracetam decreases synaptic responses in a time-, frequency- and concentration-dependent manner. Seletracetam modifies rates of presynaptic release. Seletracetam inhibits high-voltage-activated Ca2+ currents and intracellular Ca2+ increase in rat cortical neurons in vitro.

Products are for research use only. Not for human use.