NF-E4 (Acetyl Lys43) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES1124-50, ES1124-100

Citations, Manuals and MSDS Available upon request.

Background: The erythroid-specific protein encoded by this gene, and the ubiquitous transcription factor CP2, form the stage selector protein (SSP) complex, which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG (CUG) translation initiation codon, and a downstream AUG codon, results in two isoforms. While the long isoform (22 kDa) acts as an activator, the short isoform (14 kDa) has been shown to repress gamma-globin gene expression. This gene is located in an intron of the FBXL13 gene on the opposite strand. [provided by RefSeq, Jul 2008],

Alternate Name: NFE4; Transcription factor NF-E4

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized acetyl-peptide derived from the human NF-E4 around the acetylation site of K43.

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 19kD

Human Gene ID: 58160

Human SWISS Prot NO: Q86UQ8

Subcellular Location: Nucleus

Research Use Only