Preventic® Tick Collar for Dogs reaches maximum effectiveness within 48 hours. Preventic® Tick Collar for Dogs contains 9% amitraz to kill and detach ticks for up to 90 days. Do not use on puppies under 12 weeks of age. Do not use on cats. •Collars fit dogs 60 lbs and over •Provides full protection against ticks within 48 hours of placement. Stops new ticks from attaching. •Demonstrated 92% efficacy in controlling a severe tick infestation after 24 hours - versus 63% efficacy achieved by a deltamethrin collar. •Protection lasts for up to 90 days. •Makes it less likely for dogs to get tick-borne diseases. By killing and detaching ticks, Preventic® Tick Collar can reduce the risk for transmission of Lyme disease, babesiosis, and rickettsia. •Paralyzes tick mouth parts to prevent feeding. •Trusted by veterinarians for 25 years. •Water-resistant Effectiveness is not diminished if the dog gets wet. •Virtually odorless. Directions: Read entire label directions before each use. It is a violation of Federal Law to use this collar in a manner inconsistent with its labeling. Place the Preventic® collar around the dog's neck buckle and adjust for proper fit. Cut off and dispose of excess length. Do not allow dogs to play with cut-off excess. The collar must be worn tightly enough to contact skin and so that the dog cannot remove it. Activity against ticks starts within 24 hours and continues as long as the collar is worn (up to 90 days). Ticks present in the dog's environment that may reappear on the dog will not attach and will be killed in less than 24 hours. Replace collar when effectiveness diminishes. The effectiveness of the collar is not diminished by normal wetting such as rainfall however it is suggested that the collar be removed before bathing. The active ingredient is not an insecticide. Therefore use other means for the control of fleas.